The final salary or hourly wage, as applicable, paid to each candidate/applicant for this position is ultimately dependent on a variety of factors, including, but not limited to, the candidate’s/applicant’s qualifications, skills, and level of experience as well as the geographical location of the position.

Applicants must be legally authorized to work in the United States. Sponsorship not available.

Our client is seeking a Senior Scientist in Cambridge, MA.

Role Description

• As a Scientist II/Senior Scientist you will contribute to drug discovery efforts for multiple therapeutic areas including neurology and immunology. You will conduct biophysical analysis and perform recombinant protein purification for early discovery research programs. This is an exciting opportunity to contribute your expertise to the Protein Sciences team.
You like to work in an environment where you can:
• Apply your scientific expertise to provide innovative approaches for production of high-quality purified proteins across diverse protein classes, including membrane proteins and non-antibody proteins
• Use your strong communication skills to collaborate with scientific teams across the organization to advance pre-clinical drug targets.
• Engage with emerging project science and therapeutic modalities
You will contribute by:
• Purifying high quality recombinant cytosolic, secreted, membrane and refolded proteins and validating these proteins with quality control experiments such as HPLC and mass spectrometry as well as binding and enzymatic assays with other project team members.
• Performing biophysical analysis of proteins and/or protein complexes using mass spectrometry and other biophysical techniques.
• Applying your subject matter expertise to innovate and drive protein purification strategies and biophysical analysis to support our pipeline of drug discovery projects.
• Contributing to project team meetings by communicating experimental results and advising on best methods to generate protein reagents for downstream applications including but not limited to biophysical characterization, structural biology, assay development, screening, hit identification and immunization.

Skills & Requirements

Minimum Qualifications:
PhD in related field (biochemistry, chemistry, molecular & cellular biology, or biophysics) + 2-4 years’
experience, BS or MS + 6-12 years’ experience (including industry experience of 4 years)
Extensive use of mass spectrometry instruments and maintenance, as well experience with other biophysical
techniques.
Strong experience using AKTA purification platform and current knowledge of purification methods and
protocols.
Strong attention to detail, ability to multitask, and enthusiasm for learning.
Preferred Qualifications:
High proficiency with Waters BioAccord mass spectrometer or equivalent is preferred.
Understanding and application of biophysical techniques, such as light scattering (mass photometry), thermal shift assay, fluorescence spectroscopy, and others are an asset.

Knowledge of upstream and downstream processes such as molecular biology, cell culture and protein
expression, structural biology and biophysics, and/or assay development.
Familiarity with drug discovery and how protein reagents fit into the process
Appreciation of critical path activities and resource prioritization that support project progression.

Benefits/Other Compensation

This position is a contract/temporary role where Hays offers you the opportunity to enroll in full medical benefits, dental benefits, vision benefits, 401K and Life Insurance ($20,000 benefit).

Why Hays?

You will be working with a professional recruiter who has intimate knowledge of the industry and market trends. Your Hays recruiter will lead you through a thorough screening process in order to understand your skills, experience, needs, and drivers. You will also get support on resume writing, interview tips, and career planning, so when there’s a position you really want, you’re fully prepared to get it.

Nervous about an upcoming interview? Unsure how to write a new resume?

Visit the Hays Career Advice section to learn top tips to help you stand out from the crowd when job hunting.

Hays is committed to building a thriving culture of diversity that embraces people with different backgrounds, perspectives, and experiences. We believe that the more inclusive we are, the better we serve our candidates, clients, and employees. We are an equal employment opportunity employer, and we comply with all applicable laws prohibiting discrimination based on race, color, creed, sex (including pregnancy, sexual orientation, or gender identity), age, national origin or ancestry, physical or mental disability, veteran status, marital status, genetic information, HIV-positive status, as well as any other characteristic protected by federal, state, or local law. One of Hays’ guiding principles is ‘do the right thing’.
We also believe that actions speak louder than words.
In that regard, we train our staff on ensuring inclusivity throughout the entire recruitment process and counsel our clients on these principles. If you have any questions about Hays or any of our processes, please contact us.

In accordance with applicable federal, state, and local law protecting qualified individuals with known disabilities, Hays will attempt to reasonably accommodate those individuals unless doing so would create an undue hardship on the company. Any qualified applicant or consultant with a disability who requires an accommodation in order to perform the essential functions of the job should call or text 813.336.5570.

Drug testing may be required; please contact a recruiter for more information.

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